What can a system administrator do to prevent Windows users from unintentionally installing malware from USB thumb drives and DVD-ROMs that contain malicious code?

The system administrator should select Disable AutoRun and AutoPlay on network computers. Adding media (CD, DVD, USB, SD) to a workstation without first understanding its source or purpose is never a good idea because the media may be infected with malware. The malware might be referenced in the autorun.inf file. When the media is inserted in the machine, it will be automatically summoned. On optical drives with constantly changing content, user permissions are not effective. Data encryption cannot be enabled on media that is subject to change, and a BIOS/UEFI password would prevent the computer from booting.